Software Development und IT-Consulting Dr. Robert Höllering

Area

Software development mainly for chemical and pharmaceutical companies in R&D as well as in the production. Analytical software like structure and spectra searches dereplication and modification / extension of MES systems.

Databases

Oracle 8, 9, 10, 11, 12 including PL/SQL programming, Oracle database gateway, MS SQL server, SQLite, Sybase Adaptive Server Enterprise, MySQL

Languages / Technics / Testing

C++, C#, .Net, VB, PL/SQL, Scripts, web services, SOAP, .Net, MFC, Java, (g)make, Windows, Unix (Linux, Solaris, ...) and other operating systems, C, Fortran, Basic, Assembler, ...
With manual and automatic build and test procedures.
Code revision systems: CVS, SVN, SourceSave, Git

Quality Assurance

Working under conditions like:
ISO9000, 21 CFR part 11, EU Annex 11, GMP, GxP, system validation / qualification, with MT, FAT, SAT, IQ, OQ, PQ

Data Handling

Data mining, QSAR, model building, linear correlation, neural networks (BPG, Kohon)

Experience since 1981

Publications

[1] J. Gasteiger, W. Hanebeck, K.-P. Schulz, S. Bauerschmidt, R. Höllering
Automatic Analysis and Simulation of Mass Spectra
in Computer-Enhanced Analytical Spectroscopy, Vol. 4
C. L. Wilkins, (Hrsg.)
Plenum Press, New York, 1993, 97-133

[2] K.-P. Schulz, S. Bauerschmidt, R. Höllering, J. Gasteiger
Automatic Elucidation of Reactions in the Mass Spectrometer
in AIP conference proceedings 330: E.C.C.C. 1
F. Bernardi, J. L. Rivail (Hrsg.)
American Institute of Physics, Woodbury, NY, 1995, 726-733

[3] R. Höllering, J. Gasteiger, and W. Hanebeck
Simulation of Mass Spectra of Organic Compounds by Massimo
in AIP conference proceedings 330: E.C.C.C. 1
F. Bernardi, J. L. Rivail (Hrsg.)
American Institute of Physics, Woodbury, NY, 1995, 782

[4] L. Steinhauer, R. Höllering, S. Bauerschmidt, T. Kostka, J. Gasteiger,
Kinetic Calculations by the Simulation of Organic Reactions,
ZAMM (Zeitschrift für angewandte Mathematik und Mechanik), 1997, eingereicht
http://www.uni-regensburg.de/Fakultaeten/nat_Fak_I/Mennicken/gamm97/s20/steinhauer/steinhauer.html

[5] Computer Methods for the Prediction and Identification of Degradation Products of Chemicals Using IR Spectra Simulation
J. Gasteiger, T. Kostka, P. Selzer, S. Bauerschmidt, R. Höllering, L. Steinhauer
Proceed. ECO-INFORMA97, Eco-Informa Press, 1997, pp. 509-513

[6] R. Höllering
Simulation von Massenspektren und Entwicklung eines Systems zur Reaktionsvorhersage
Dissertation, Universität Erlangen-Nürnberg 1998

[7] A Unified Approach to Exposure Assessment by Computer Models for Degradation Reactions and Soil Accumulation: The Triazine Herbicide Example
H. Behrendt, J. Altschuh, S. Sixt, J. Gasteiger, R. Höllering, T. Kostka
Chemosphere 1999, 38, 1811-1823.

[8] Simulation of Organic Reactions: From the Degradation of Chemicals to Combinatorial Synthesis
Robert Höllering, Johann Gasteiger*, Larissa Steinhauer, Klaus-Peter Schulz, and Achim Herwig
J. Chem. Inf. Comput. Sci., 40 (2), 482 -494, 2000.

[9] Computer-Assited Synthesis and Reaction Planning in Combinatorial Chemistry
J. Gasteiger, M. Pförtner, M. Sitzmann, R. Höllering, O. Sacher, T. Kostka, N. Karg
Persp. Drug Discov. Design 2000, 20, 245-264.

[10] Decision Support Systems for Chemical Structure Representation, Reaction Modeling, and Spectra Simulation
J. Gasteiger, S. Bauerschmidt, U. Burkard, M.C. Hemmer, A. Herwig, A. von Homeyer, R. Höllering, T. Kleinöder, T. Kostka, C. Schwab, P. Selzer, L. Steinhauer
SAR & QSAR in Environm. Res. 2002 ,13 (1), 89-110.

Softwareentwicklung und IT-Consulting
Dr. Robert Höllering
Sandstraße 78a
D-50226 Frechen

Tel.: +49 / (0)2234 / 9 81 81 83
Fax: +49 / (0)2234 / 9 81 82 88
http://www.robert-hoellering.de/
Email: soft@robert-hoellering.de

USt-IdNr.: DE253606852